When creating Uploader Droplets in Uploader Creator you can turn on compression, so that files will be compressed before they are uploaded to the WebNative server. When files arrive, a custom script could be written to decompress files on the WebNative server.

You can specify whether to compress all files into one archive, or whether to compress each file individually.

Compression settings can also be specified, and you can choose from between speed and ratio based compression.