Both the PrintSure desktop client and the browser applet client are supported on a number of platforms. PrintSure client software still supports Apple Mac OS 9 and is optimised for Apple Mac OS X and Windows 2000+.

All customers are covered from a single licence of PrintSure and installation of the right version of software is automatic with the help of the DevZeroG "100% web" installer.

PrintSure server can be installed on a number of platforms, including Windows, Apple Mac OS X (Workstation and Server) and Red Hat Fedora Linux. Other Linux flavours, such as Red Hat Enterprise and Suse, as well as operating systems from the UNIX family, e.g. Sun Solaris and SGI IRIX can also be utilised on an individual basis.